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College of Science and Engineering
Chemistry & Biochemistry

Dr. Tomisin Happy Ogunwa

Lecturer/Post Doctoral Scholar

Ogunwa

Office: CHEM 313

Email: ywn3@txstate.edu

Phone: 

Fax: (512) 245-1436

 

Educational Background

  • B.S., Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Nigeria (2010)
  • M.S., Biochemistry, University of Benin, Benin city, Nigeria (2015)
  • Ph.D., Environmental Science, Nagasaki University, Japan (2019) 

Mentor: Prof. Miyanishi Takayuki

  • Postdoctoral Fellow (Takeda Science Foundation), Soka University, Hachioji Tokyo (2020-2021) 

Mentor: Prof. Maruta Shinsaku

Research Scholar (Postdoctoral) Texas State University, San Marcos (2021- till date) 

Mentor: Dr. Ryan Peterson

 

Honors & Academic Awards

  • Distinction student (Class of 2010)
  • Japanese MEXT scholarship 2016 – 2019
  • Atomwise (AIMS) award, 2019
  • Takeda Science Foundation (International Fellowship Programs for foreign researchers) 2020 – 2021 

 

Areas of Interest

Biological Chemistry
Protein Biochemistry and enzymology 
Natural Product Chemistry

Computational Chemistry 

 

 

Publications

Salihu AS, Salleh WMNHW, Ogunwa TH (2023). Chemical composition, acetylcholinesterase inhibition and molecular docking studies of essential oil from Knema hookeriana Warb. (Myristicaceae). Natural Product Research 28:1 – 6. doi: 10.1080/14786419.2023.2184359

Ebokaiwe AP, Ushang OR, Ogunwa, T H, Kikiowo B, and Olusanya O. (2022). Quercetin attenuates cyclophosphamide induced-immunosuppressive indoleamine 2,3-dioxygenase in the hippocampus and cerebral cortex of male Wister rats. Journal of Biochemical and Molecular Toxicology, 36(11): e23179. doi.org/10.1002/jbt.23179.
 

Alrazi I, Ogunwa TH, Kolawole AO, Elekofehinti OO, Omotuyi OI, Miyanishi T, and Maruta S. (2021). Kolaflavanone, a biflavonoid derived from medicinal plant Garcinia, is an inhibitor of mitotic kinesin Eg5. Journal of biochemistry, 170(5), 611–622. https://doi.org/10.1093/jb/mvab083.

Ogunwa TH, Taii K, Sadakane K, Kawata Y, Maruta S, and Miyanishi T. (2019) Morelloflavone as a novel inhibitor of mitotic kinesin Eg5. Journal of Biochemistry., 166(2), 129–137. https://doi.org/10.1093/jb/mvz015.

Omotuyi IO, Oyekanmi N, David S, Ayodeji AO, Ogunwa TH, Adelakun SN. (2019) T-705-modified ssRNA in complex with Lassa virus nucleoprotein exhibits nucleotide splaying an increased water influx into the RNA-binding pocket. Chemical Biology and Drug Design, 93(4): 544-555. https://doi.org/10.1111/cbdd.13451.
 

Oyewale MR, Seidu KT, Ogunbusola EM, Osundahunsi OF, Ogunwa TH, Akele O, Adejoro DO. (2020). Nutritional composition and sensory quality of packaged ofe-owerri: a major traditional soup in Nigeria. Current Nutrition and Food Science. 16, 1439 – 1448. http://www.eurekaselect.com/article/105532.

Ogunwa TH, Laudadio E, Galeazzi R, and Miyanishi T. (2019) Insights into the molecular mechanisms of Eg5 inhibition by (+)-morelloflavone. Pharmaceuticals, 12 (2), 58: 1-19. https://doi.org/10.3390/ph12020058.

Salleh WMNHW and Ogunwa TH. (2019) Insights into the inhibitory mechanism and molecular interaction of novel alkaloids from Beilschmiedia glabra with lipoxygenase and acetylcholinesterase. Journal of Theoretical and Computational Chemistry, 18(8):1950039. https://www.worldscientific.com/doi/abs/10.1142/S021963361950038X

Ogunwa TH, Fasimoye RY, Adeyelu TT. (2019) Studies on the interaction mechanisms of Garcinia kolaviron constituents with selected diabetes and neurodegenerative disease targets. Journal of proteins and proteomics, 10, 221-234. https://doi.org/10.1007/s42485-019-00021-x.

Ogunwa TH. (2019) Interaction studies of Angelica polymorpha and Beilschmiedia pulverulenta phytochemicals with acetylcholinesterase as anti-Alzheimer’s disease target. International Journal of Computational Biology and Drug Design, 12(1): 80-99. https://www.inderscienceonline.com/doi/abs/10.1504/IJCBDD.2019.098180